Opportunity Information: Apply for PA 19 122
The NIH Midcareer Investigator Award in Patient-Oriented Research (K24), listed as PA 19-122, is a discretionary NIH grant mechanism intended to strengthen the patient-oriented research (POR) workforce by supporting established, mid-career clinician-scientists. The central goal is to buy protected time for qualified health-professional doctorates so they can both (1) sustain and expand their own patient-oriented research programs and (2) serve as active, hands-on research mentors for the next generation of clinical investigators, especially clinical residents, clinical fellows, and junior clinical faculty. In practice, this award is meant to help a productive clinician-investigator step back from competing clinical or administrative duties enough to focus on rigorous human-subjects research and to build a structured mentoring environment that reliably develops trainees into independent researchers.
A defining feature of this specific FOA is its clinical trial limitation. It is explicitly for applicants whose proposed research plan does not include leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial as the lead investigator. The intent is to support patient-oriented research that may involve human participants and clinical investigation, but not in a way where the K24 awardee is the person directing a trial as the primary trial leader under this application. At the same time, the FOA does allow applicants to gain research experience connected to a clinical trial led by another investigator, which can still be valuable for mentorship, exposure to trial operations, and contributing to patient-oriented science without being the responsible leader. If an applicant intends to lead a clinical trial or ancillary trial, the announcement instructs them to use the companion K24 FOA designed for independent clinical trials instead.
Eligibility spans a wide range of U.S.-based organizations and institutions that can host and support the awardee and their mentoring activities. Eligible applicant organizations include state, county, city, township, and special district governments; federally recognized Native American tribal governments and certain other tribal organizations; public housing authorities/Indian housing authorities; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (when not classified as institutions of higher education); for-profit organizations other than small businesses; small businesses; and other eligible entities. The announcement also highlights additional eligible organization types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. While the FOA references “non-domestic (non-U.S.) entities,” it clarifies that non-U.S. institutions and non-U.S. components of U.S. organizations are not eligible to apply; however, “foreign components” (as NIH defines them in the NIH Grants Policy Statement) are allowed, meaning a U.S. applicant organization may include certain international elements within the project when permitted under NIH policy.
From an administrative standpoint, the funding instrument is a grant and the activity category is listed under education, environment, and health, reflecting the career development and mentoring emphasis alongside patient-oriented research. The opportunity is administered by the National Institutes of Health and is associated with multiple CFDA numbers (including 93.113, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.361, 93.837, 93.838, 93.839, 93.840, 93.846, 93.855, 93.866), which typically indicates that multiple NIH Institutes or Centers may participate or that the mechanism is used across several program areas. The source record notes an original closing date of 2020-05-07 and a creation date of 2018-12-20; it does not provide an award ceiling or expected number of awards in the supplied text, implying those details either vary by participating Institute/Center, budget justification, or are specified elsewhere in the full FOA.
Overall, this K24 opportunity is best understood as a mid-career “time and mentorship” award: it supports a proven clinician-investigator to protect substantial effort for patient-oriented research while building a robust mentoring track record. The emphasis is not just on the candidate’s science, but on their role as a multiplier for the clinical research pipeline, with a clear boundary that the proposed work under this particular FOA cannot be structured around the applicant leading an independent clinical trial.Apply for PA 19 122
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.361, 93.837, 93.838, 93.839, 93.840, 93.846, 93.855, 93.866.
- This funding opportunity was created on 2018-12-20.
- Applicants must submit their applications by 2020-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 19 122) also looked into and applied for these:
| Funding Opportunity |
|---|
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Required) Apply for PA 19 131 Funding Number: PA 19 131 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed) Apply for PA 19 132 Funding Number: PA 19 132 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| U.S.-China Program for Biomedical Collaborative Research (R01 Clinical Trial Optional) Apply for RFA CA 19 009 Funding Number: RFA CA 19 009 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $150,000 |
| Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed) Apply for PAR 19 158 Funding Number: PAR 19 158 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (Clinical Trials Not Allowed R25) Apply for PAR 19 164 Funding Number: PAR 19 164 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) Apply for PA 19 187 Funding Number: PA 19 187 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (R25 Clinical Trial Not Allowed) Apply for PAR 19 197 Funding Number: PAR 19 197 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Building Interdisciplinary Research Careers in Women's Health (BIRCWH); K12 Clinical Trial Optional Apply for RFA OD 19 020 Funding Number: RFA OD 19 020 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $600,000 |
| Basic and Translational Research on Adducts in Cancer Risk Identification and Prevention (R21 Clinical Trial Optional) Apply for PAR 19 252 Funding Number: PAR 19 252 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Influences on Aging: Effects of Extreme Weather and Disaster Events on Aging Populations (R01 Clinical Trial Optional) Apply for PAR 19 250 Funding Number: PAR 19 250 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Basic and Translational Research on Adducts in Cancer Risk Identification and Prevention (R01 Clinical Trial Optional) Apply for PAR 19 251 Funding Number: PAR 19 251 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Apply for PAR 19 275 Funding Number: PAR 19 275 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Mechanism for Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trial Not Allowed) Apply for RFA ES 19 011 Funding Number: RFA ES 19 011 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Apply for RFA OD 19 029 Funding Number: RFA OD 19 029 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) Apply for PA 20 047 Funding Number: PA 20 047 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) Apply for PA 20 025 Funding Number: PA 20 025 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Data Repository (U24 - Clinical Trials Not Allowed) Apply for PAR 20 089 Funding Number: PAR 20 089 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed) Apply for PAR 20 097 Funding Number: PAR 20 097 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R01 Clinical Trials Not Allowed) Apply for PAR 20 165 Funding Number: PAR 20 165 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R21 Clinical Trials Not Allowed) Apply for PAR 20 168 Funding Number: PAR 20 168 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
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