Opportunity Information: Apply for RFA AI 17 044
The funding opportunity titled "Limited Competition: Revision Applications for International Centers of Excellence for Malaria Research (U19 Clinical Trial Optional)" (RFA-AI-17-044) is a National Institutes of Health (NIH) cooperative agreement aimed specifically at investigators who already hold active International Centers of Excellence for Malaria Research (ICEMR) awards. Rather than launching an entirely new ICEMR program, this announcement is designed as a limited competition revision mechanism, meaning it supports add-on or expansion activities that build directly on the existing ICEMR platforms, personnel, field sites, and surveillance systems already established in malaria-endemic countries.
At its core, the purpose of the FOA is to fund additional studies that evaluate the real-world impact of in-country, approved malaria vector control and prevention interventions. The emphasis is on understanding how these interventions affect malaria incidence (new infections over time), prevalence (how many people are infected at a point in time), and transmission dynamics (how malaria moves through human and mosquito populations). The work is intended to translate into human health outcomes, using or strengthening malaria surveillance systems that ICEMRs have already put in place, rather than starting from scratch. In practical terms, the FOA is trying to capitalize on the substantial baseline data and operational capacity created by ICEMRs, and then use those assets to answer timely program-relevant questions about whether prevention strategies are working as intended in specific settings.
The FOA supports studies that are observational and/or implementation-oriented, with an overall goal of measuring intervention impact under field conditions and improving understanding of what drives success or failure. The announcement explicitly structures proposed projects into three study types. Study Type 1 is a Controlled study, which generally implies a more structured comparison design (for example, comparing intervention and control areas or periods under a defined protocol). Study Type 2 is an Observational study, which typically relies on measurement without assigning interventions, often using surveillance or cohort data to detect associations and trends as interventions roll out. Study Type 3 is an Implementation study, which focuses on how interventions are delivered in practice, including operational barriers, coverage, adherence, fidelity to program guidelines, and factors affecting uptake and sustainability. Applicants are allowed to propose projects for one of each study type, giving ICEMRs flexibility to combine complementary approaches, such as pairing surveillance-based impact estimates with implementation analyses that explain why certain outcomes occurred.
Administratively, the award mechanism is a cooperative agreement (U19), which signals that NIH expects to have substantial programmatic involvement in the conduct and oversight of the funded work compared to a standard research grant. The FOA is categorized under Health and is associated with CFDA number 93.855. The eligible applicant organizations are public and state-controlled institutions of higher education, and because it is a limited competition revision, the practical eligibility is further constrained to currently funded ICEMR investigators seeking revisions to their active awards. The opportunity was created on December 22, 2017, with an original closing date of May 30, 2018. The award ceiling is listed as $200,000, and NIH anticipated making about 12 awards under this announcement.
Overall, this FOA is best understood as a targeted, time-sensitive funding supplement to the ongoing ICEMR enterprise, intended to quickly generate evidence on the effectiveness and operational performance of malaria vector control and prevention interventions that countries have already approved and are deploying. By leveraging established ICEMR surveillance systems and baseline measurements, the program aims to produce actionable findings about intervention impact on malaria burden and transmission, while also capturing the implementation realities that determine whether public health strategies actually deliver the expected benefits in the field.Apply for RFA AI 17 044
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Revision Applications for International Centers of Excellence for Malaria Research (U19 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
- This funding opportunity was created on Dec 22, 2017.
- Applicants must submit their applications by May 30, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- The number of recipients for this funding is limited to 12 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education.
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