Opportunity Information: Apply for RFA CA 24 032
This funding opportunity, titled "Single Source: NCI National Clinical Trials Network - Canadian Collaborating Clinical Trials Network (U10 Clinical Trial Required)" (RFA-CA-24-032), is a National Cancer Institute (NCI) solicitation under the National Institutes of Health (NIH) that uses a cooperative agreement mechanism (U10). The central aim is to support an institution or organization that can maintain and operate a Canadian Collaborating Clinical Trials Network as an integrated partner within the NCI National Clinical Trials Network (NCTN). In practical terms, the award is meant to keep a Canada-based network functioning at a level that allows it to participate alongside the U.S. NCTN in large, multi-site cancer clinical trials, with the awardee serving as a key conduit for Canadian trial participation rather than acting as a standalone program.
A major focus of the opportunity is enabling Canada to function as a full partner in the NCTN trial ecosystem. That means supporting the infrastructure, coordination, and operational capabilities needed for large-scale, multi-institution clinical trials that span multiple sites and stakeholders. The Canadian collaborating network is expected to contribute not only trial participation and site coordination, but also specialized regulatory expertise and oversight tailored to Canada. This regulatory component is emphasized in the description, reflecting the reality that cross-border trials require careful alignment with national requirements, ethics review expectations, and other compliance processes specific to conducting NCTN trials in Canada.
Because this is a cooperative agreement (U10), applicants should expect substantial programmatic involvement from NCI compared with a typical grant. Cooperative agreements are generally used when the funding agency anticipates an active partnership with the recipient in guiding or coordinating the work, which fits the stated intent that the Canadian network will operate as a full partner with the U.S. network in executing major trials. The title also indicates "Clinical Trial Required," signaling that the funded activities are expected to include clinical trial conduct as defined by NIH requirements, rather than being limited to planning, training, or purely observational work.
Eligibility is broad and includes both U.S. and non-U.S. entities, with specific conditions. Non-domestic (non-U.S.) entities (foreign organizations) are explicitly eligible to apply, which aligns with the Canadian focus of the network. At the same time, non-domestic components of U.S. organizations are not eligible to apply, meaning a U.S. institution cannot apply through an overseas branch or component. Foreign components, as defined by the NIH Grants Policy Statement, are allowed, which generally means that a U.S. applicant may include a foreign component in the project under NIH rules, even though the non-domestic component itself is not the applicant organization.
The opportunity is categorized as discretionary funding and falls under NIH, with NCI as the agency. The associated CFDA numbers are 93.394 and 93.395, both of which relate to NCI programs. The notice was created on 2024-10-09, and the original closing date listed is 2025-02-24. The source data provided does not specify an award ceiling or expected number of awards, so applicants would need to rely on the full NOFO details and NIH guidance for budget expectations, project period length, and any constraints or benchmarks that NCI may apply to this particular "single source" competition.
Overall, the opportunity is best understood as support for a Canada-centered operational hub that can reliably plug Canadian institutions into NCTN cancer trials, while also managing the additional regulatory and oversight demands that arise when implementing U.S.-led or U.S.-coordinated network trials within the Canadian clinical research environment.Apply for RFA CA 24 032
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Single Source: NCI National Clinical Trials Network - Canadian Collaborating Clinical Trials Network (U10 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394, 93.395.
- This funding opportunity was created on 2024-10-09.
- Applicants must submit their applications by 2025-02-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Independent school districts, Public housing authorities/Indian housing authorities, Others.
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