Opportunity Information: Apply for RFA DK 22 003
The National Institutes of Health (NIH) funding opportunity "Promoting Organ and Tissue Donation Among Health Disparity Populations (R01 - Clinical Trial Optional)" (Funding Opportunity Number RFA-DK-22-003) is a discretionary grant program designed to boost research that addresses gaps in organ and tissue donation among diverse, underserved, and health disparity populations. The overall aim is practical and outcomes-focused: generate evidence about why donation rates are lower in certain communities, test clear hypotheses about the barriers involved, and support the creation and evaluation of new strategies that can meaningfully increase participation in both living and deceased organ and/or tissue donation.
The FOA encourages research that looks closely at individual-level drivers of donation and transplantation need, including attitudes, beliefs, knowledge, trust, motivations, and behaviors that shape whether someone registers as a donor, discusses donation with family, considers living donation, or navigates systems connected to donation and transplant. At the same time, it emphasizes that individual choices do not happen in a vacuum, so applicants are also encouraged to examine broader social determinants of health that can produce or reinforce disparities. That can include factors like access to accurate information, health literacy, language barriers, cultural norms, religious concerns, historical and present-day medical mistrust, experiences of discrimination, socioeconomic constraints, differences in healthcare access, and policy or institutional practices that affect donation opportunities and decision-making.
A major theme in this opportunity is moving beyond description toward action. NIH indicates it will support studies that test hypotheses about the real-world challenges preventing higher donation rates in diverse communities and that lay the groundwork for novel interventions. Those interventions could be educational, community-based, health system-based, or policy-informed, as long as they are designed with relevance to underserved populations and are capable of producing measurable improvements. Because the mechanism is an R01 and clinical trials are optional, the opportunity can support a wide range of rigorous research designs, from observational and mixed-methods work that identifies causal pathways and modifiable barriers, to intervention development and testing where appropriate.
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities, reflecting an intention to bring in researchers and partners with strong community connections. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations (other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; and small businesses. The FOA also explicitly highlights additional applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American Tribal Governments (other than federally recognized), and U.S. territories or possessions.
The announcement is restrictive regarding foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed. In other words, applications must be fully domestic in terms of applicant organization and project components.
From the administrative details provided, the awarding agency is NIH, the funding instrument is a grant, and the activity category is listed under food and nutrition/health with CFDA number 93.847. The original closing date was 2022-10-27, and an award ceiling is listed as $150,000 in the source data. The opportunity was created on 2022-05-24. Overall, the FOA is centered on producing actionable research that helps communities experiencing disparities overcome barriers to organ and tissue donation, with the long-term goal of increasing donation participation and improving equity in transplant-related outcomes.Apply for RFA DK 22 003
- The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Promoting Organ and Tissue Donation Among Health Disparity Populations (R01 - Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on 2022-05-24.
- Applicants must submit their applications by 2022-10-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the name and funding opportunity number for this grant?
The opportunity is titled "Promoting Organ and Tissue Donation Among Health Disparity Populations (R01 - Clinical Trial Optional)" and the Funding Opportunity Number (FON) is RFA-DK-22-003.
Which agency is offering this funding opportunity?
The awarding agency is the National Institutes of Health (NIH).
What type of funding instrument is this?
This is a discretionary grant program, and the funding instrument is a grant.
What activity category is this opportunity listed under?
The activity category is listed under food and nutrition/health, with CFDA number 93.847.
What is the main purpose of this FOA?
The FOA is intended to boost practical, outcomes-focused research that addresses gaps in organ and tissue donation among diverse, underserved, and health disparity populations. It aims to generate evidence about why donation rates are lower in certain communities and support strategies that can meaningfully increase participation in living and/or deceased organ and tissue donation.
What kinds of research questions does NIH want applicants to address?
NIH is looking for studies that test clear hypotheses about barriers and real-world challenges that reduce organ and tissue donation rates in diverse communities. The FOA emphasizes moving beyond describing disparities to identifying modifiable barriers and producing evidence that supports actionable solutions.
Is the focus limited to living donation, deceased donation, or both?
The FOA supports research relevant to both living and deceased organ and/or tissue donation.
What individual-level factors are encouraged as topics of study?
The FOA encourages research on individual-level drivers tied to donation and transplant need, including attitudes, beliefs, knowledge, trust, motivations, and behaviors that influence whether someone registers as a donor, discusses donation with family, considers living donation, or navigates systems connected to donation and transplant.
Does the FOA encourage research beyond individual attitudes and behaviors?
Yes. NIH emphasizes that individual choices are shaped by broader conditions, so applicants are encouraged to examine social determinants of health and other systemic factors that can create or reinforce disparities.
What broader social determinants or structural barriers are specifically mentioned?
Examples listed include access to accurate information, health literacy, language barriers, cultural norms, religious concerns, historical and present-day medical mistrust, experiences of discrimination, socioeconomic constraints, differences in healthcare access, and policy or institutional practices that affect donation opportunities and decision-making.
Does NIH expect projects to include interventions?
The FOA strongly emphasizes actionable work and indicates support for studies that lay the groundwork for novel interventions. Interventions can be educational, community-based, health system-based, or policy-informed, as long as they are relevant to underserved populations and can produce measurable improvements.
Are clinical trials required under this opportunity?
No. The mechanism is R01 and clinical trials are optional, meaning projects may include clinical trials where appropriate but are not required to do so.
What kinds of study designs can be supported?
Because it is an R01 with clinical trials optional, the FOA can support a wide range of rigorous designs, including observational studies, mixed-methods research that identifies causal pathways and modifiable barriers, and intervention development and testing where appropriate.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and governmental entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations (other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; and small businesses.
Are specific institution types explicitly highlighted as encouraged or included?
Yes. The FOA explicitly highlights additional applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American Tribal Governments (other than federally recognized), and U.S. territories or possessions.
Can non-U.S. (foreign) organizations apply for this grant?
No. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply.
Can a U.S. organization include a non-U.S. component or site?
No. Non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed. Applications must be fully domestic in terms of the applicant organization and project components.
What is the award ceiling shown for this opportunity?
The source data lists an award ceiling of $150,000.
When was the opportunity created and what was the closing date listed?
The opportunity was created on 2022-05-24, and the original closing date listed was 2022-10-27.
What is the long-term goal of the funded research?
The long-term goal is to increase organ and tissue donation participation in communities experiencing disparities and improve equity in transplant-related outcomes by producing evidence and strategies that reduce barriers and increase meaningful participation.
What does NIH mean by moving “beyond description toward action” in this FOA?
Based on the FOA summary provided, NIH is prioritizing research that does more than document disparities. Projects should test hypotheses about real-world barriers and generate evidence that can inform, develop, or evaluate strategies capable of producing measurable improvements in donation participation among underserved groups.
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