Promoting Organ and Tissue Donation Among Health Disparity Populations (R01 - Clinical Trial Optional) | RFA DK 22 003

Opportunity Information: Apply for RFA DK 22 003

The National Institutes of Health (NIH) funding opportunity "Promoting Organ and Tissue Donation Among Health Disparity Populations (R01 - Clinical Trial Optional)" (Funding Opportunity Number RFA-DK-22-003) is a discretionary grant program designed to boost research that addresses gaps in organ and tissue donation among diverse, underserved, and health disparity populations. The overall aim is practical and outcomes-focused: generate evidence about why donation rates are lower in certain communities, test clear hypotheses about the barriers involved, and support the creation and evaluation of new strategies that can meaningfully increase participation in both living and deceased organ and/or tissue donation.

The FOA encourages research that looks closely at individual-level drivers of donation and transplantation need, including attitudes, beliefs, knowledge, trust, motivations, and behaviors that shape whether someone registers as a donor, discusses donation with family, considers living donation, or navigates systems connected to donation and transplant. At the same time, it emphasizes that individual choices do not happen in a vacuum, so applicants are also encouraged to examine broader social determinants of health that can produce or reinforce disparities. That can include factors like access to accurate information, health literacy, language barriers, cultural norms, religious concerns, historical and present-day medical mistrust, experiences of discrimination, socioeconomic constraints, differences in healthcare access, and policy or institutional practices that affect donation opportunities and decision-making.

A major theme in this opportunity is moving beyond description toward action. NIH indicates it will support studies that test hypotheses about the real-world challenges preventing higher donation rates in diverse communities and that lay the groundwork for novel interventions. Those interventions could be educational, community-based, health system-based, or policy-informed, as long as they are designed with relevance to underserved populations and are capable of producing measurable improvements. Because the mechanism is an R01 and clinical trials are optional, the opportunity can support a wide range of rigorous research designs, from observational and mixed-methods work that identifies causal pathways and modifiable barriers, to intervention development and testing where appropriate.

Eligibility is broad and includes many types of U.S.-based organizations and governmental entities, reflecting an intention to bring in researchers and partners with strong community connections. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations (other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; and small businesses. The FOA also explicitly highlights additional applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American Tribal Governments (other than federally recognized), and U.S. territories or possessions.

The announcement is restrictive regarding foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed. In other words, applications must be fully domestic in terms of applicant organization and project components.

From the administrative details provided, the awarding agency is NIH, the funding instrument is a grant, and the activity category is listed under food and nutrition/health with CFDA number 93.847. The original closing date was 2022-10-27, and an award ceiling is listed as $150,000 in the source data. The opportunity was created on 2022-05-24. Overall, the FOA is centered on producing actionable research that helps communities experiencing disparities overcome barriers to organ and tissue donation, with the long-term goal of increasing donation participation and improving equity in transplant-related outcomes.

• The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Promoting Organ and Tissue Donation Among Health Disparity Populations (R01 - Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
• This funding opportunity was created on 2022-05-24.
• Applicants must submit their applications by 2022-10-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $150,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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