NIA Revision and Resubmission Program Project Applications (P01 Clinical Trial Optional) | PAR 18 030

Opportunity Information: Apply for PAR 18 030

The NIA Revision and Resubmission Program Project Applications opportunity (Funding Opportunity Number PAR 18 030) is a National Institutes of Health discretionary grant program run by the National Institute on Aging (NIA) under CFDA 93.866. It is focused on Program Project (P01) applications and is designed specifically for two situations: (1) revision applications to program project awards that are already funded by NIA, and (2) resubmissions of program project applications that were previously submitted but not funded, including resubmissions of unfunded revision requests. In plain terms, this announcement is meant to help research teams either expand an existing NIA-funded P01 program in a structured way or improve and resubmit a previously unsuccessful P01 application so it can be reconsidered.

A key expectation is that proposed work must align with NIA's mission areas, meaning the scientific focus should be relevant to aging and age-related health and disease. For revision requests in particular, the application is expected to go beyond simply continuing what is already funded. The revision should add something new: either an expansion of one or more existing projects within the larger P01, or the creation of one or more entirely new projects that fit coherently within the program project framework. The idea is that the parent P01 remains the foundation, but the revision introduces additional, mission-relevant science that strengthens or broadens the overall program.

There is also an important timing and budget boundary for revisions: a revision application cannot extend the project period beyond the end date of the currently funded parent P01 award. So even if the new or expanded work is substantial, the request has to fit within the remaining time window of the active P01. That condition is central to how these revisions are planned, since applicants must scale the proposed added work to what can realistically be completed and managed before the parent award ends.

The funding instrument is a grant, and the activity category is health. The announcement is described as "P01 Clinical Trial Optional," which indicates that clinical trials may be included when appropriate, but they are not required. Applicants would still need to follow NIH rules and the specific FOA instructions regarding human subjects research and clinical trial definitions if they propose clinical trial activities, but the core point is flexibility: the P01 can be clinical-trial oriented or not, depending on the science.

Eligibility is broad and includes many typical NIH-eligible organizations. Eligible applicant types listed include state, county, city or township governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and Native American tribal governments (federally recognized) as well as tribal organizations other than federally recognized tribal governments. The announcement also explicitly highlights additional categories of eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Practically, this signals NIA's openness to applications from a wide range of institutional settings, including organizations that are often underrepresented in major research funding portfolios.

Foreign involvement is allowed only in a limited, specific way. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, "foreign components" as defined by the NIH Grants Policy Statement are allowed. That usually means a U.S.-based applicant can include certain scientifically justified international elements (such as collaborations, data collection sites, or other project components abroad) as part of the overall program, as long as they meet NIH policy requirements and are properly described and approved.

From the administrative details provided, the original closing date listed is 2019-07-12 and the creation date is 2017-10-30. The award ceiling and expected number of awards are not specified in the provided source text, which implies applicants would need to refer to the full FOA and NIH budget guidance for the P01 mechanism to understand typical funding levels, budgeting conventions, and constraints. Overall, the opportunity is best understood as a pathway for NIA-supported P01 teams to add new mission-relevant scientific work within the remaining life of an active program project, and for investigators with unfunded P01 submissions (or unfunded revisions) to revise their approach and come back with a stronger resubmission for NIA consideration.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIA Revision and Resubmission Program Project Applications (P01 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
• This funding opportunity was created on 2017-10-30.
• Applicants must submit their applications by 2019-07-12. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 18 030

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