Opportunity Information: Apply for RFA DA 17 019

The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), is seeking an applicant to run a Coordinating Center (CC) for its HIV/AIDS and Substance Use Cohorts Program under a U24 cooperative agreement (Funding Opportunity Number RFA-DA-17-019; CFDA 93.279). The purpose of this opportunity is to strengthen and connect a set of NIDA-funded longitudinal cohort studies focused on HIV/AIDS in the context of both injection and non-injection substance use. These cohorts collectively generate long-term participant data and valuable biological specimens, and they cover a wide range of research areas, from basic immunology and virology to prevention, treatment, and the study of co-morbidities and co-infections that commonly occur alongside HIV and substance use.

At its core, the opportunity reflects NIDA's view that the existing cohorts are a powerful shared resource, but that they can deliver even more impact if supported by a central hub. The Coordinating Center is meant to make it easier for the cohort investigators to work together, and also to open the door for productive collaborations with outside researchers who are not directly funded under the cohort program. In practical terms, that means the CC would be expected to help organize and streamline cross-cohort activities, improve access to cohort-generated data and specimens, and reduce administrative and logistical barriers that often slow down multi-site or multi-cohort science.

A major expected function of the Coordinating Center is the creation and maintenance of a virtual repository. While the announcement does not spell out every technical detail, the intent is clear: the CC should provide an organized, centralized way to catalog, manage, and facilitate access to data resources and bio-specimen information coming from the participating cohorts. This kind of virtual repository typically supports discovery (so investigators can learn what data/specimens exist), governance (so requests are reviewed consistently and transparently), and coordination (so materials and data are used efficiently and in ways that maximize scientific value).

The CC is also expected to facilitate leadership and operations of the cohorts Steering Committee (SC). The SC is described as consisting of representatives from the NIDA-funded cohorts along with NIDA staff, and the CC would serve as the operational backbone that helps the committee function effectively. In a cooperative agreement structure like a U24, this generally implies active involvement and partnership with NIH/NIDA program staff, with shared responsibilities in planning, priority-setting, and oversight rather than a fully independent, investigator-directed model.

This funding opportunity is discretionary and uses a cooperative agreement mechanism, signaling that NIDA anticipates substantial programmatic involvement during the period of performance. The program is aimed at coordinating the cohorts that are currently funded by NIDA, rather than creating brand-new cohorts. Only one award was anticipated (Expected Awards: 1), emphasizing that NIDA was looking for a single entity to serve as the central coordinating hub for the entire network. The original closing date listed for the opportunity was November 14, 2016, and the posting indicates no stated award ceiling in the summarized fields provided.

Eligibility is broad across many types of US-based organizations and governments. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those specific nonprofit categories); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly highlights several categories of institutions and organizations as eligible or of interest, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and US territories or possessions.

Foreign eligibility is explicitly restricted. Non-domestic (non-US) entities and non-domestic components of US organizations are not eligible to apply, and foreign components, as defined by the NIH Grants Policy Statement, are not allowed. In other words, while the work may address globally relevant HIV and substance use questions, the applicant organization and the proposed project components must be based within the permitted US framework.

Overall, the opportunity is designed to increase the scientific value and real-world utility of NIDA's investment in HIV/substance use cohort research by building shared infrastructure: coordination across cohorts, governance and facilitation for collaboration, a virtual repository to improve access and efficiency, and structured support for the steering committee that guides the network. The end goal is to speed up discovery and improve the quality and reach of research on HIV pathogenesis, prevention, and treatment in the context of substance use, while also enabling broader investigator-initiated projects that can leverage the cohorts' data and biospecimen resources.

  • The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Coordinating Center for the HIV/AIDS and Substance Use Cohorts Program (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
  • This funding opportunity was created on 2016-09-07.
  • Applicants must submit their applications by 2016-11-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for RFA DA 17 019

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